Which prostaglandin in stomach

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy Continue. Twitter Facebook. This Issue. January Donald E. Wilson, MD. Author Affiliations Chicago. Access through your institution. Add or change institution.

Save Preferences. The physiological role of prostaglandins is still being elucidated. There is now strong evidence that endogenous prostaglandins modulate acid secretion by blocking the histamine-stimulated increase in cyclic AMP within the parietal cell.

This function is probably controlled by intraluminal pH. It is likely that mucus and bicarbonate secretion by both stomach and duodenum are influenced by endogenous prostaglandins. New York, Raven Press, pp — New York, Raven Press, , pp Hepatogastroenterology —, Effect of non-steroidal anti-inflammatory compounds.

Scand J Gastroenterol 19 Suppl —77, Gastroenterology —65, Surgery —76, Johansson C, Kollberg B, Nordeman R: Protective effect of prostaglandin E2 in the gastrointestinal tract during indomethacin treatment of rheumatic diseases. Gastroenterology — Tokyo, Biomed Res Found, , pp — Aust NZ J Med —, Peskar BM: Effect of carbenoxolone on prostaglandin synthesizing and metabolizing enzymes and correlation with gastric mucosal carbenoxolone concentrations.

Scand J Gastroenterol 15 Suppl —, Scand J Gastroenterol 19 Suppl —, Histologic, ultrastructural and functional changes in normal gastric mucosa induced by antacids. Gastroenterology , Download references. Institute of Physiology, Academy of Medicine, ul.

Grzegorzecka 16, , Krakow, Poland. You can also search for this author in PubMed Google Scholar. Reprints and Permissions. Konturek, S. Prostaglandins in pathophysiology of peptic ulcer disease. Digest Dis Sci 30, S—S